- What is creatinine?
- Normal values
- Why does it increase
- Creatinine clearance
- Low creatinine
- How to lower high creatinine
In most cases, the main reasons for consultation related to the results obtained after conducting a blood test is the appearance of high levels of transaminases, cholesterol and triglycerides. The emergence of high levels of risk may also be a cause for concern. high creatinine , not being so usual decreased levels of creatinine (that is, below what is considered normal).
With regard to the high creatinine in itself, basically consists in a residue of both mass and muscle activity . Since the kidneys are responsible for filtering and eliminating it through urine, the measurement of their values in the blood analysis is useful to know if the kidneys are functioning correctly , or if on the contrary there could be some pathology or a malfunction of these organs.
Since their production depends directly on the modification of muscle mass, many doctors usually consider that Creatinine levels actually vary very little , so if there is no pathology, its values tend to remain stable. Thus A level of creatinine that increases with the passage of time may be indicative of damage to the kidney . But when are there low levels of creatinine?
What is low creatinine and what are its causes?
When in a blood test we find high blood creatinine values can actually be an indication that they are causing damage to the kidneys. But when their values are the opposite, ie they are diminished and are below what is considered normal depending on the sex and age of the person, their causes are usually not so clear.
Basically The decrease in blood creatinine levels is caused by the decrease in muscle mass , which can be a sign of certain diseases that cause the decrease of muscle mass, such as:
- Muscular dystrophy : group of inherited disorders that cause muscle weakness and loss of muscle tissue, which get worse over time.
- Myasthenia gravis : neuromuscular disorder consisting of a type of autoimmune disorder in which the body produces antibodies that block muscle cells, whereas healthy muscle tissue is actually a harmful substance, which causes weakness of the muscles.
It is also possible to find levels of low creatinine in people bedridden or who they stay long periods of time in bed (for example after being hospitalized), since muscle mass tends to decrease.
The same goes for the old people , Given the muscle mass tends to decrease with age .
What creatinine values are considered low?
Although creatinine values they usually vary a bit between different laboratories, usually there is a low or decreased creatinine when its values are below normal . The average values are the following:
- Creatinine values in adult men : between 0.7 and 1.3 mg / dl
- Creatinine values in adult women : between 0.5 to 1.2 mg / dl
- Creatinine values in children : between 0.2 to 1 mg / dl
Therefore, any value located below 0.7 mg / dl in men, 0.5 mg / dl in women and 0.2 mg / dl is considered diminished and the medical specialist will inquire about its causes after returning to repeat the analysis in a certain time (for example at 3 or 6 months).